All You Must Know About PRP Treatment The blood cells that form the bone marrow is called as platelets and they are containing packets of protein in charge for blood clotting and wound healing. The moment that the platelets are released into the bloodstream from the marrow, they have a circulating lifespan of 7 to 10 days. Whenever there is an acute injury, you can be sure that there is going to be the accumulation of platelets at site. There is sequence of events that take place with the formation of cloth as well as the released of growth factors. In the said area, these said growth factors will be attracting different blood cells. Some other growth factors as well as cells are assisting with the healing process. It is sometimes considered to use additional human thrombin and calcium chloride in order to stimulate the release of growth factors in most instances. While bovine thrombin are being used as well, there’ve been several accounts of hypersensitivity reactions to small number of patients. PRP or Platelet Rich Plasma is actually a concentrate of the entire body that contains a minimum of 1 million platelets per 6cc’s. Preferably, platelet concentration in 3 to 5 million range is better because of higher concentration of platelets means there are more growth factors and faster healing.
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It was in American Journal of Sports Medicine where one of the early papers that describe the use of PRP was established. The researchers presented non randomized study of 20 patients who have chronic lateral epicondylitis or tennis elbow. For the next 2 months, the patients were closely monitored after receiving PRP treatment and there is around 60 percent improvement PRP treated group than the 16 percent in the control group.
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This said treatment has been studied as well for Achilles tendon problems, which has produced mixed results. Dutch study was published in American Medical Association back in 2010 that involves 54 patients who showed no statistical difference between the groups that were treated with exercise and saline and groups receiving PRP treatments. On the other hand, there’s been some criticism with regards to the study design and other studies reporting some positive results with PRP in treating Achilles tendonitis. Other conditions for which PRP treatment was known to be used are patellar tendonitis, rotator cuff tendonitis of shoulder, gluteus medius tendonitis of hip, plantar fasciitis and even osteoarthritis. When PRP is applied after needle tenotomy or a type of procedure wherein a small incision is made to the part of tendon damage via ultrasound guidance using a small needle, it is creating an acute injury to the said part. This acute injury is actually what stimulating acute inflammatory response, that will then cause the release of platelet’s growth as well as healing factors.